E45 is a trusted British skincare brand owned by Swedish pharmaceutical company Karo Healthcare AB, offering licensed emollient creams, lotions, itch relief treatments, specialist eczema, dermatitis and psoriasis creams, facial care, sun care, and the new HydroCell technology range. With licensed medicines including E45 Cream, E45 Itch Relief Cream, and HC45 Hydrocortisone Cream, E45 is stocked across nine major UK retailers including Boots, Superdrug, Tesco, ASDA, Sainsbury’s, and Amazon. Products are consistent eBay UK and Amazon UK bestsellers backed by five named medical expert contributors and decades of dermatological trust.
Headquarters
Klara Norra Kyrkogata 33, SE-111 22 Stockholm, Sweden.
Authentic Distributors
1. Karo Healthcare UK Direct ✅ (consumersupport@karohealthcare.com — confirmed exact consumer support email)
2. Karo Healthcare AB Corporate ✅ (karohealthcare.com — confirmed Swedish parent company)
3. UK Pharmacy Wholesale Networks ⚠️ (verify specific named distributor before proceeding — note: Boots, Superdrug, Tesco, ASDA, Sainsbury's, Morrisons, Waitrose, Ocado are retail stockists, NOT wholesale distributors)
Professional Notes for FBA Sellers
✅ PHARMACEUTICAL-GRADE REGULATORY STATUS —
E45 Cream, E45 Itch Relief Cream, and HC45
Hydrocortisone Cream are confirmed LICENSED
MEDICINES under UK pharmaceutical regulation —
stronger clinical credibility than cosmetic
skincare brands, similar to Corsodyl and
Sudocrem researched earlier
✅ CONFIRMED EXISTING AMAZON RELATIONSHIP —
Amazon is directly linked as a retail partner
on the brand's own homepage — important
context before pursuing FBA wholesale
sourcing given this existing direct relationship
⚠️ Always confirm "Always read the label"
compliance for licensed medicine products —
Amazon has specific listing requirements for
pharmaceutical/OTC medicine products that
may require additional category approval
✅ Always request authorization letter LOA
and confirm invoices show your registered
business name for Amazon compliance —
especially important for regulated medicine
products
✅ HC45 Hydrocortisone Cream (£4.49) with active
ingredient "hydrocortisone acetate BP 1.0% w/w"
represents a distinct OTC pharmacy category
beyond standard emollient creams — different
Amazon category requirements may apply
✅ HydroCell™ new range with in vivo testing
evidence represents a genuine innovation
opportunity — premium body serum spray format
is distinct from E45's traditional cream/lotion
heritage, useful for premium Amazon listing positioning